Observational prospects for gravitational waves from hidden or dark chiral phase transitions

We study the gravitational wave (GW) signature of first-order chiral phase transitions ($\chi$PT) in strongly interacting hidden or dark sectors. We do so using several effective models in order to reliably capture the relevant non-perturbative dynamics. This approach allows us to explicitly calculate key quantities characterizing the $\chi$PT without having to resort to rough estimates. Most importantly, we find that the transition's inverse duration $\beta$ normalized to the Hubble parameter $H$ is at least two orders of magnitude larger than typically assumed in comparable scenarios, namely $\beta/H\gtrsim\mathcal{O}(10^4)$. The obtained GW spectra then suggest that signals from hidden $\chi$PTs occurring at around 100 MeV can be in reach of LISA, while DECIGO and BBO may detect a stochastic GW background associated with transitions between roughly 1 GeV and 10 TeV. Signatures of transitions at higher temperatures are found to be outside the range of any currently proposed experiment. Even though predictions from different effective models are qualitatively similar, we find that they may vary considerably from a quantitative point of view, which highlights the need for true first-principle calculations such as lattice simulations.Comment: 35 pages, 9 figures. Extended discussion and updated calculation of gravitational wave spectra, main results unchanged; references added; matches published versio

Exact solution of a model DNA-inversion genetic switch with orientational control

DNA inversion is an important mechanism by which bacteria and bacteriophage switch reversibly between phenotypic states. In such switches, the orientation of a short DNA element is flipped by a site-specific recombinase enzyme. We propose a simple model for a DNA inversion switch in which recombinase production is dependent on the switch state (orientational control). Our model is inspired by the fim switch in Escherichia coli. We present an exact analytical solution of the chemical master equation for the model switch, as well as stochastic simulations. Orientational control causes the switch to deviate from Poissonian behaviour: the distribution of times in the on state shows a peak and successive flip times are correlated.Comment: Revised version, accepted for publicatio

The distribution of total vitamin b12 holotranscobalamin and the active vitamin b12 fraction in the first 5 weeks postpartum

Introduction Total vitamin B12 levels decrease significantly during pregnancy and recover to normal values within 8-week postpartum. Holotranscobalamin (holoTC) reflects the active part of vitamin B12 and has been shown to remain constant during pregnancy and postpartum. A mechanism of redistribution of vitamin B12 is suggested, with a shift toward holoTC if there is insufficient total vitamin B12 available. Our objective was to examine vitamin B12 deficiency and the active vitamin B12 fraction in postpartum women. Methods Total vitamin B12 and holoTC were measured in 171 women within 48 hours (T0) and at 5 weeks (T5) postpartum. Vitamin B12 deficiency was defined as total vitamin B12 < 180 pmol/L or holoTC <32 pmol/L. The active vitamin B12 fraction was defined as holoTC/total vitamin B12. Results Without intervention, vitamin B12 deficiency based on both serum total vitamin B12 and holoTC changed from 75% and 60%, to respectively 10% and 6% at T5. The fraction of active vitamin B12 was significant higher in vitamin B12 deficient women at both time points and across time (P < .0001 and P = .002). A high fraction of active vitamin B12 was only present in women with total vitamin B12 deficiency at T0. At T5, no high vitamin B12 fraction was found. Conclusion The changes in total vitamin B12 levels seem to be based on a physiological changes rather than vitamin B12 deficiency. The results of this study confirm the hypothesis that a shift toward the metabolic active vitamin B12 (holoTC) occurs in women with insufficient available total vitamin B12

Searching for “Illegal” Junk in the Trunk: Underlying Intentions of (Cr)Immigration Controls in Schengen’s Internal Border Areas

Criminal Justice: Legitimacy, accountability, and effectivit

Eradication of invasive birds from tropical oceanic islands: lessons learned from studies of common mynas Acridotheres tristis

Feare, C., Greenwell, P., Edwards, H., Taylor, J., Van der Woude, J